If you are following more than 100 people on Twitter, you know how hard it is to keep track of who said what. The best application I have found for this is TweetDeck. TweetDeck is an Adobe AIR application (which means you have to download the AIR software onto your computer) that lets you see in table form at least 3 columns. The default columns are “Friends”, “Replies”, and “Direct Messages.”  You can build your own column  as a Group (the tab is at the top of the application). Fo example, my Group are the followers I am most interested in. I named the Group, and then selected the Twitter names that I wanted in the group. The program does the rest.

You can also change the colors of the application.

I highly recommend this desktop app for keeping up on what is happening day to day on Twitter.